My lab uses a combination of computational biology and high throughput genomics techniques to identify functional elements in the genome. I am particularly interested in sequence elements that regulate RNA splicing. Specific projects that move beyond identifying splicing signals include 1) understanding how particular arrangements of sequence elements are read by the splicing machinery, 2) identifying mutations/polymorphisms that disrupt splicing in the human population, and 3) investigating the evolution of gene expression signals.

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a reading list of relevant papers ...